Formamidopyrimidine DNA Glycosylase Fpg Raw Material Enzyme

• Environmental Protection: Yes
• Classification: Coenzyme
• Transport Package: Carton
• Specification: test
• Trademark: ABIOM
• Origin: China
• Model NO.: Formamidopyrimidine DNA Glycosylase Fpg
• HS Code: 3507901000
• Production Capacity: 100000

Product Description

 

Product Description

Fpg (formamidopyrimidine fapy-DNA glycosylase) (also known as 8-oxoguanine DNA glycosvlase) acts both as a N-eglycosvlase andan AP-lyase. The N-glycosylase activity releases damaged purines from double stranded DNA, generating an apurinic (AP site). TheAP-lyase activity cleaves both 3' and 5 to the AP site thereby removing the AP site and leaving a 1 base gap. Some of the damaged base:recognized and removed by Fpg include 7, 8-dihydro-8-oxoguanine (8-oxoguanine), 8-oxoadenine, fapy-guanine, methy-fapy-guaninefapy-adenine, aflatoxin B1-fapy-guanine, 5-hydroxy-cytosine and 5-hydroxy-uracil

 

Product Parameters

Applications

Comet assay;

Research on DNA damage and repair;

SNP analysis;

Alkaline precipitation;

Alkali helix.

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