Ngs Library Formamidopyrimidine DNA Glycosylase Fpg Raw Material Enzyme

• CAS No.: Gsp9181, Gsp9182, Gsp9183, Gsp9184
• Formula: N/a
• EINECS: N/a
• Classification: Biochemical Reagents
• Grade: N/a
• Specific Usage: For Biological Purpose
• Model NO.: Formamidopyrimidine DNA Glycosylase Fpg
• Content: Standard
• Usage: Laboratory Reagents
• Source: N/a
• Habit Appellation: Fine Chemicals
• Application: Scientific Research, Health
• Property: Enzyme & Coenzyme
• Product Name: Formamidopyrimidine DNA Glycosylase (Fpg)
• Feature: High Purity, Simple, Efficient
• Storage: -25°c-15°c
• Appearance: Colorless Liquid
• Applications: Scientific Research, PCR
• Shelf Life: 18 Months
• Payment: Tt
• Delivery: 5-15 Days
• Packing: Box
• Transport Package: Carton Package
• Specification: 50µ 100µ 200µ 1000µ
• Trademark: ABIOM
• Origin: Guangdong, China
• HS Code: 3507901000
• Production Capacity: 5000 Boxes/Month

Product Description

Product Description

Formamidopyrimidine DNA Glycosylase (Fpg) (8U/µL)

Fpg (formamidopyrimidine [fapy]-DNA glycosylase) (also known as 8-oxoguanine DNA glycosylase) acts both as a N-glycosylase and an AP-lyase. The N-glycosylase activity releases damaged purines from double stranded DNA, generating an apurinic (AP site). The AP-lyase activity cleaves both 3'and 5'to the AP site thereby removing the AP site and leaving a 1 base gap. Some of the damaged bases recognized and removed by Fpg include 7, 8-dihydro-8-oxoguanine (8-oxoguanine), 8-oxoadenine, fapy-guanine, methy-fapy-guanine, fapy-adenine, aflatoxin B1-fapy-guanine, 5-hydroxy-cytosine and 5-hydroxy-uracil.



Applications:

1. Comet assay;

2. Research on DNA damage and repair;

3. SNP analysis;

4. Alkaline precipitation;

5. Alkali helix.